The American Academy of Neurology’s “Practice Guideline: Treatment of Restless Legs Syndrome in Adults” includes 4 recommendations on which medication to prescribe when targeting concomitant psychiatric symptoms among patients with restless legs syndrome (RLS). According to the guideline, which agent is recommended for patients with RLS for whom clinicians want to target concomitant anxiety?
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When targeting concomitant psychiatric symptoms among your patients with RLS, the guideline recommends you use gabapentin enacarbil for overall mood (moderate evidence) and pramipexole for depression and anxiety, in the context of moderate to severe RLS-related mood disturbance (weak evidence).
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